Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a condition characterized by an abnormal heart rhythm (arrhythmia). As the heart rate increases in response to physical activity or emotional stress, it can trigger an abnormally fast heartbeat called ventricular tachycardia.
What is CPVT (polymorphic ventricular tachycardia)?
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a genetic disorder that causes an abnormally fast and irregular heart rhythm in response to physical activity or emotional stress.
What is CPTV syndrome?
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a genetic disorder that causes an abnormally fast and irregular heart rhythm in response to physical activity or emotional stress. Signs and symptoms include light-headedness, dizziness, and fainting. Symptoms most often develop between 7 to 9 years of age.
What is the rate of incidence for CPVT?
About 1 out of every 10,000 people have CPVT. You may be more likely to have this condition if there is a history of premature death in your family, since undiagnosed CPVT can cause such sudden deaths. Signs of CPVT can start as early as childhood.
Are HFrEF and hfmref the same disease with different severities?
The data are most robust in HFrEF, but similar benefit was observed in HFmrHF. These relevant findings suggesting that HFrEF and HFmrEF are just the same disease with different severities, are put into context in an Editorial by Douglas Mann from the Washington University School of Medicine in Saint Louis, Missouri, USA. 10
Is CPVT an autosomal dominant disorder?
When CPVT results from mutations in the RYR2 gene, it follows an autosomal dominant inheritance pattern, which means one copy of the altered gene in each cell is sufficient to cause the disorder. In about half of cases, an affected person inherits an RYR2 gene mutation from one affected parent.
